Biotherapy is the use of natural, living organisms to treat or diagnose illness.

Medical Maggot are indicated for debriding non-healing necrotic skin and soft tissue wounds, including pressure ulcers, venous stasis ulcers, neuropathic foot ulcers and non-healing traumatic or post surgical wounds

Larval Therapy

There are indications that may influence the bacterial burden within the wound and may be considered as a method of debridement in a necrotic or infected wound. There are potential advantages and disadvantages of larval therapy. 

Advantages of larval therapy are:

Rapid and selective debridement

Reduced bacterial burden

Possible control of MRSA

Possible micromassage effect stimulating healing

Possible chemical stimulation to healing

No report toxicity or allergenicity

Disadvantages of larval therapy are:


Slower than sharp or surgical debridement 

Not suitable for all wounds

Effectiveness limited by environment (wound pH, fluid and oxygen)

Aesthetic aspects for patients and staff


Some other examples of biotherapy are use of medicinal maggots to debride (clean) wounds, medicinal leeches to treat venous congestion and ichthyotherapy (fish therapy) to treat exfoliative skin conditions.



Dr. Craig H. Thomajan, DPM, FACFAS, FAENS
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Founder and Managing Partner of Austin Foot and Ankle Specialists