Prolotherapy with Autologous Conditioned Plasma

Injectable autologous blood products is a new, safe and very effective biosurgical method which has created a growing interest for use in a number of foot and ankle therapies. The healing effects of plasma are supported by growth factors released by platelets. These growth factors induce a healing process wherever they are applied. When activated they release growth and anti-inflammatory factor proteins. In locomotive organ tissues (cartilage, tendons, ligaments, bones and skin) they support healing, regenerative and repair processes.

Essential function of platelets is evident every time when the tissue integrity of the human body is broken. After every scratch, cut etc. a set of complicated reactions of our organisms is launched in order to stop bleeding and restoration of structures within the injury. And growth and anti-inflammatory factors released from activated platelets considerably enhance the whole healing process.

Features and Benefits

Producing ACP (Autologous Conditioned Plasma) with the Arthrex ACP System can be performed within minutes in our office as an out patient procedure. Unlike other industry platelet rich plasma (PRP) systems that can take up to 45 minutes to process the blood for application. This technique delays treatment and increasing the cost of the in office procedure.

The ACP System can be used in our clinic or under sterile conditions in an OR setting. The unique double syringe design allows for convenient and safe handling, as the whole preparation process takes place in a closed system.

Concentrating these factors into tissues causes:

  • Anti-inflammatory processes
  • Acceleration of the healing process
  • Prevention of disease transfer into a chronic condition
  • Regeneration and reparation of damaged tissue structures

Conditions for the use of Autologous Conditioned Plasma:

  • Plantar Fasciitis/Fasciosis
  • Achilles Tendonitis/Tendonosis
  • Acute and Chronic Ankle Strain/Sprains

If you feel that you have exhausted all conservative treatment protocols and have suffered with lingering pain, consider visiting with our doctors at Austin Foot and Ankle Specialists to discuss the use of ACP prior to having a surgical management.

Growth Factors in PRP

PRP contains various growth factors that play important roles in cell proliferation, chemotaxis, cell differentiation, and angiogenesis concentrations. The basic cytokines identified include platelet-derived growth factor, vascular endothelial growth factor, hepatocyte growth factor. The clinical benefit of these growth factors contained in PRP or BMC for the treatment of pathologies of the foot or ankle is derived from these biological properties. The molecular mechanisms of action and preclinical studies supporting the use of these growth factors is covered elsewhere in this special edition of Operative Techniques in Sports Medicine and therefore will not be reviewed herein.

Prolotherapy

Dr. Craig H. Thomajan, DPM, FACFAS, FAENS
Founder and Managing Partner of Austin Foot and Ankle Specialists